Phospho-IRS1 (Ser636) Polyclonal AntibodyE-AB-20908
Product Category: Phospho/Acetyl/Methyl
Description: May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit.
Research Areas: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal transduction, Tags & Cell Markers
Size: 200 uL
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
Gene ID: 3667
Immunogen: Synthesized peptide derived from human IRS-1 around the phosphorylation site of Ser636
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Observed MW: 150kDa
Storage: Store at -20C. Avoid freeze / thaw cycles.
Cellular Localization: Cytosol,Nucleus,Plasma Membrane,caveola,insulin receptor complex,plasma membrane,Other locations:cytoplasm,intracellular membrane-bounded organelle
Product Link: https://www.elabscience.com/p-phospho_irs1_(ser636)_polyclonal_antibody-25497.html
Manaul Link: https://www.elabscience.com/viewpdf-25497-elabscience-E-AB-20908.PDF