Phospho-SH-PTP2 (Tyr580) Polyclonal AntibodyE-AB-21127
Product Category: Phospho/Acetyl/Methyl
Description: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene.
Research Areas: Cancer, Neuroscience, Signal transduction
Size: 200 uL
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
Gene ID: 5781
Immunogen: Synthesized peptide derived from human SH-PTP2 around the phosphorylation site of Tyr580
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Observed MW: 70kDa
Storage: Store at -20C. Avoid freeze / thaw cycles.
Cellular Localization: Cytoplasm.
Product Link: https://www.elabscience.com/p-phospho_sh_ptp2_(tyr580)_polyclonal_antibody-25716.html
Manaul Link: https://www.elabscience.com/viewpdf-25716-elabscience-E-AB-21127.PDF