Phospho-SMAD1 (Ser465) Polyclonal AntibodyE-AB-21128
Product Category: Phospho/Acetyl/Methyl
Description: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Signal transduction, Stem cells
Size: 200 uL
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
Gene ID: 4086
Immunogen: Synthesized peptide derived from human Smad1 around the phosphorylation site of Ser465
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Observed MW: 60kDa
Storage: Store at -20C. Avoid freeze / thaw cycles.
Cellular Localization: Cytoplasm. Nucleus. Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4. Co-localizes with LEMD3 at the nucleus inner membrane.
Product Link: https://www.elabscience.com/p-phospho_smad1_(ser465)_polyclonal_antibody-25717.html
Manaul Link: https://www.elabscience.com/viewpdf-25717-elabscience-E-AB-21128.PDF