Phospho-PAK1 (Ser204) Polyclonal Antibody

Phospho-PAK1 (Ser204) Polyclonal Antibody

E-AB-21232

Regular price $399.00 $349.00 You Pay

Supplier: Elabscience
Product Category: Phospho/Acetyl/Methyl
Description: The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2.
Research Areas: Cancer, Cell Biology, Signal transduction
Size: 200 uL
Concentration: 1mg/mL
Applications: WB,IHC-p,ELISA
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000
Clonality: Polyclonal
Clone No:
SwissProt: Q13153
Gene ID: 5058
Reactivity: Human,Mouse,Rat
Host: Rabbit
Isotype: IgG
Immunogen: Synthesized peptide derived from human PAK? around the phosphorylation site of S204.
Formulation: PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Purification: Affinity purification
Conjugation: Unconjugated
Observed MW: 65kDa
Storage: Store at -20C. Avoid freeze / thaw cycles.
Cellular Localization: Cytoplasm. Cell junction>focal adhesion. Recruited to focal adhesions upon activation.

Product Link: https://www.elabscience.com/p-phospho_pak1_(ser204)_polyclonal_antibody-25821.html
Manaul Link: https://www.elabscience.com/viewpdf-25821-elabscience-E-AB-21232.PDF