Phospho-RIPK2 (Ser176) Polyclonal AntibodyE-AB-21233
Product Category: Phospho/Acetyl/Methyl
Description: This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli.RIPK2 (Receptor Interacting Serine/Threonine Kinase 2) is a Protein Coding gene. Diseases associated with RIPK2 include Lymphoproliferative Syndrome, X-Linked, 2 and Human Granulocytic Anaplasmosis. Among its related pathways are IL-1 signaling pathway and Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways. GO annotations related to this gene include protein homodimerization activity and protein kinase activity. An important paralog of this gene is RIPK4.
Research Areas: Cancer, Cell Biology, Metabolism, Immunology, Signal transduction
Size: 200 uL
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
Gene ID: 8767
Immunogen: Synthesized peptide derived from human RIP2 around the phosphorylation site of Ser176
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Observed MW: 70kDa
Storage: Store at -20C. Avoid freeze / thaw cycles.
Cellular Localization: Cytoplasm.
Product Link: https://www.elabscience.com/p-phospho_ripk2_(ser176)_polyclonal_antibody-25822.html
Manaul Link: https://www.elabscience.com/viewpdf-25822-elabscience-E-AB-21233.PDF