Phospho-MEF2A (Ser408) Polyclonal Antibody

Phospho-MEF2A (Ser408) Polyclonal Antibody

E-AB-21264

Regular price $399.00 $349.00 You Pay

Supplier: Elabscience
Product Category: Phospho/Acetyl/Methyl
Description: Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation.
Research Areas: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Neuroscience
Size: 200 uL
Concentration: 1mg/mL
Applications: WB,IHC-p,IF,ELISA
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000
Clonality: Polyclonal
Clone No:
SwissProt: Q02078
Gene ID: 4205
Reactivity: Human,Mouse,Rat
Host: Rabbit
Isotype: IgG
Immunogen: Synthesized peptide derived from human MEF-2 around the phosphorylation site of Ser408
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Conjugation: Unconjugated
Observed MW: 55kDa
Storage: Store at -20C. Avoid freeze / thaw cycles.
Cellular Localization: Nucleus.

Product Link: https://www.elabscience.com/p-phospho_mef2a_(ser408)_polyclonal_antibody-25853.html
Manaul Link: https://www.elabscience.com/viewpdf-25853-elabscience-E-AB-21264.PDF