Phospho-Caldesmo (Ser789) Polyclonal AntibodyE-AB-21275
Product Category: Phospho/Acetyl/Methyl
Description: This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Research Areas: Cancer, Cardiovascular, Signal transduction
Size: 200 uL
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
Gene ID: 800
Immunogen: Synthesized peptide derived from human Caldesmon around the phosphorylation site of Ser789
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Observed MW: 80kDa
Storage: Store at -20C. Avoid freeze / thaw cycles.
Cellular Localization: Cytoplasm
Product Link: https://www.elabscience.com/p-phospho_caldesmon_(ser789)_polyclonal_antibody-25864.html
Manaul Link: https://www.elabscience.com/viewpdf-25864-elabscience-E-AB-21275.PDF