Phospho-p120 (Tyr228) Polyclonal AntibodyE-AB-21284
Product Category: Phospho/Acetyl/Methyl
Description: Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.
Research Areas: Cancer, Signal transduction, Stem cells
Size: 200 uL
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
Gene ID: 1500
Immunogen: Synthesized peptide derived from human p120 around the phosphorylation site of Tyr228
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Observed MW: 108kDa
Storage: Store at -20C. Avoid freeze / thaw cycles.
Cellular Localization: Cytoplasm. Nucleus. Cell membrane. Interaction with GLIS2 promotes nuclear translocation (By similarity). NANOS1 induces its translocation from sites of cell-cell contact to the cytoplasm.
Product Link: https://www.elabscience.com/p-phospho_p120_(tyr228)_polyclonal_antibody-25873.html
Manaul Link: https://www.elabscience.com/viewpdf-25873-elabscience-E-AB-21284.PDF