Phospho-Histone H2A (Thr121) Polyclonal AntibodyE-AB-21298
Product Category: Phospho/Acetyl/Methyl
Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Research Areas: Epigenetics and Nuclear Signaling
Size: 200 uL
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000
Gene ID: 8329/8332/8336/8969/3012/8335/3013/85235/723790/8337/92815
Immunogen: Synthesized peptide derived from human Histone H2A around the phosphorylation site of Thr121
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Storage: Store at -20C. Avoid freeze / thaw cycles.
Cellular Localization: Extracellular region or secreted,extracellular exosome,Nucleus,nuclear chromatin,nucleus,Other locations:nucleosome
Product Link: https://www.elabscience.com/p-phospho_histone_h2a_(thr121)_polyclonal_antibody-25887.html
Manaul Link: https://www.elabscience.com/viewpdf-25887-elabscience-E-AB-21298.PDF