Phospho-TGF ? Receptor I (Ser165) Polyclonal Antibody
Product Category: Phospho/Acetyl/Methyl
Description: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta.
Research Areas: Cancer, Cardiovascular, Metabolism, Signal transduction, Stem cells
Size: 200 uL
Recommended Dilutions: WB 1:500-2000, IHC 1:50-300, IF 1:50-300
Gene ID: 7046
Immunogen: Synthesized peptide derived from human TGF? RI around the phosphorylation site of Ser165
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Storage: Store at -20C. Avoid freeze / thaw cycles.
Cellular Localization: Cytoplasm