Phospho-Histone H3 (Thr45) Polyclonal AntibodyE-AB-21319
Product Category: Phospho/Acetyl/Methyl
Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Size: 200 uL
Recommended Dilutions: WB 1:3000-20000
Gene ID: 8350/8351/8352/8353/8354/8355/8356/8357/8358/8968
Immunogen: Synthetic Peptide
Formulation: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Purification: Affinity purification
Observed MW: 15-17kDa
Storage: Store at -20C. Avoid freeze / thaw cycles.
Cellular Localization: Extracellular region or secreted,extracellular exosome,extracellular region,Nucleus,nuclear chromosome,nuclear chromosome, telomeric region,nuclear nucleosome,nucleoplasm,nucleus,Other locations:nucleosome,protein complex
Product Link: https://www.elabscience.com/p-phospho_histone_h3_(thr45)_polyclonal_antibody-25375.html
Manaul Link: https://www.elabscience.com/viewpdf-25375-elabscience-E-AB-21319.PDF