Phospho-VCP (Ser352) Polyclonal AntibodyE-AB-21415
Product Category: Phospho/Acetyl/Methyl
Description: The protein encoded by this gene is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. This protein, as a structural protein, is associated with clathrin, and heat-shock protein Hsc70, to form a complex. It has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation.
Research Areas: Cancer, Metabolism, Neuroscience, Signal transduction
Size: 200 uL
Recommended Dilutions: WB 1:500-1:2000, ELISA 1:5000
Gene ID: 7415
Immunogen: Synthesized peptide derived from human VCP around the phosphorylation site of Ser352
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Observed MW: 85kDa
Storage: Store at -20C. Avoid freeze / thaw cycles.
Cellular Localization: Cytoplasm>cytosol. Nucleus. Present in the neuronal hyaline inclusion bodies specifically found in motor neurons from amyotrophic lateral sclerosis patients. Present in the Lewy bodies specifically found in neurons from Parkinson disease patients.
Product Link: https://www.elabscience.com/p-phospho_vcp_(ser352)_polyclonal_antibody-41132.html
Manaul Link: https://www.elabscience.com/viewpdf-41132-elabscience-E-AB-21415.PDF