Phospho-MAP3K7 (Ser439) Polyclonal AntibodyE-AB-21462
Product Category: Phospho/Acetyl/Methyl
Description: Component of a protein kinase signal transduction cascade. Mediator of TRAF6 and TGF-beta signal transduction. Activates IKBKB and MAPK8 in response to TRAF6 signaling. Stimulates NF-kappa-B activation and the p38 MAPK pathway. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK, but not that of NF-kappa-B.
Research Areas: Cancer, Cardiovascular, Immunology, Signal transduction
Size: 200 uL
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000
Gene ID: 6885
Immunogen: Synthesized peptide derived from human Tak1 around the phosphorylation site of Ser439
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Observed MW: 67kDa
Storage: Store at -20C. Avoid freeze / thaw cycles.
Cellular Localization: Cytosol,Endosome membrane,Nucleus,Ada2/Gcn5/Ada3 transcription activator complex,nucleus,Plasma Membrane
Product Link: https://www.elabscience.com/p-phospho_map3k7_(ser439)_polyclonal_antibody-41129.html
Manaul Link: https://www.elabscience.com/viewpdf-41129-elabscience-E-AB-21462.PDF