Phospho-MAPKAPK5 (Thr182) Polyclonal AntibodyE-AB-21464
Product Category: Phospho/Acetyl/Methyl
Description: The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported.
Research Areas: Cancer
Size: 200 uL
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000
Gene ID: 8550
Immunogen: Synthesized peptide derived from human PRAK around the phosphorylation site of Thr182
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Observed MW: 60kDa
Storage: Store at -20C. Avoid freeze / thaw cycles.
Cellular Localization: Cytoplasm. Nucleus. Also observed in the nucleus.
Product Link: https://www.elabscience.com/p-phospho_mapkapk5_(thr182)_polyclonal_antibody-41137.html
Manaul Link: https://www.elabscience.com/viewpdf-41137-elabscience-E-AB-21464.PDF