Phospho-Histone H1 (Thr17) Polyclonal AntibodyE-AB-21485
Product Category: Phospho/Acetyl/Methyl
Description: May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling.
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Size: 200 uL
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
Gene ID: 3009/3007/3008
Immunogen: Synthesized peptide derived from human Histone H1 around the phosphorylation site of Thr17
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Observed MW: 31kDa
Storage: Store at -20C. Avoid freeze / thaw cycles.
Cellular Localization: Extracellular region or secreted,extracellular exosome,Nucleus,nuclear heterochromatin,nuclear nucleosome,nucleus
Product Link: https://www.elabscience.com/p-phospho_histone_h1_(thr17)_polyclonal_antibody-41094.html
Manaul Link: https://www.elabscience.com/viewpdf-41094-elabscience-E-AB-21485.PDF