Di-Methyl-Histone H3 (Lys27) Monoclonal Antibody

Di-Methyl-Histone H3 (Lys27) Monoclonal Antibody

E-AB-22059

Regular price $399.00 $349.00 You Pay

Supplier: Elabscience
Product Category: Phospho/Acetyl/Methyl
Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Size: 200 uL
Concentration: 1mg/mL
Applications: WB,IP
Recommended Dilutions: WB 1:1000-3000, IP 1:100-1:300
Clonality: Monoclonal
Clone No: Clone:2J1
SwissProt: P68431,Q71DI3,P84243
Gene ID: 8350/8351/8352/8353/8354/8355/8356/8357/8358/8968
Reactivity: Human,Mouse,Rat
Host: Mouse
Isotype: IgG
Immunogen: Synthetic Peptide
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.4
Purification: Protein A purification
Conjugation: Unconjugated
Observed MW: 15kDa
Storage: Store at -20C. Avoid freeze / thaw cycles.
Cellular Localization: Extracellular region or secreted,extracellular exosome,extracellular region,Nucleus,nuclear chromosome,nuclear chromosome, telomeric region,nuclear nucleosome,nucleoplasm,nucleus,Other locations:nucleosome,protein complex

Product Link: https://www.elabscience.com/p-di_methyl_histone_h3_(lys27)_monoclonal_antibody-24711.html
Manaul Link: https://www.elabscience.com/viewpdf-24711-elabscience-E-AB-22059.PDF