Anti-Mouse CD8 Monoclonal Antibody (PE/Cy7 conjugated)E-AB-2253
Product Type: monoclonal antibody for FC
Description: CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked ? and ? chains that form the ?(CD8a)/?(CD8b) heterodimer and ?/? homodimer. The CD8 ?/? heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR ?/? T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 ?/? homodimer is expressed on a subset of ?/? TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.
Resarch Areas: Immunology, Stem cells
Size: 100 ug
Clone No: YTS169.4
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis (The amount of the reagent is suggested to be used ? 0.25 µg /10^6 cells in 100 µl). Since applications vary, the appropriate dilutions must be determined for individual use.
Isotype: Rat IgG2b
Formulation: PBS with 0.09% NaN3, 0.2% BSA, PH7.2
Storage: Keep as concentrated solution. Store at 4°C and protected from prolonged exposure to light. Do not freeze.
Product Link: https://www.elabscience.com/p-anti_mouse_cd8_monoclonal_antibody_(pe_cy7_conjugated)-39504.html
Manual Link: https://www.elabscience.com/viewpdf-39504-elabscience-E-AB-2253.PDF