Anti-Mouse/Human CD45R/B220 monoclonal antibody (PE conjugated)E-AB-2271
Product Type: monoclonal antibody for FC
Description: CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.
Resarch Areas: Immunology, Stem cells
Size: 200 ug
Clone No: RA3-6B2
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis (The amount of the reagent is suggested to be used ? 0.25 µg /10^6 cells in 100 µl). Since applications vary, the appropriate dilutions must be determined for individual use.
Isotype: Rat IgG2a
Formulation: PBS with 0.09% NaN3, 0.2% BSA, PH7.2
Storage: Keep as concentrated solution. Store at 4°C and protected from prolonged exposure to light. Do not freeze.
Product Link: https://www.elabscience.com/p-anti_mouse_human_cd45r_b220_monoclonal_antibody_(pe_conjugated)-39522.html
Manual Link: https://www.elabscience.com/viewpdf-39522-elabscience-E-AB-2271.PDF