Insulin Monoclonal AntibodyE-AB-27218
Product Type: monoclonal antibody
Clone No: Clone:740
Description: Insulin is a peptide hormone,produced by beta cells of the pancreas,and is central to regulating carbohydrate and fat metabolism in the body. It participates in glucose utilization,protein synthesis and in the formation and storage of neutral lipids. Insulin is synthesized as a precursor molecule,proinsulin,which is processed prior to secretion. A- and B-peptides are joined together by a disulfide bond to form insulin,while the central portion of the precursor molecule is cleaved and released as the C-peptide. Defects in insulin results in type 1 diabetes mellitus. Insulin may also exist 36 kDa form corresponding to the hexameric insulin form.
Research Areas: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal transduction
Size: 200 uL
Gene ID: 3630
Recommended Dilutions: IHC 1:500-1:5000
Immunogen: Fusion protein of Insulin
Formulation: PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Purification: Protein A purification
Calculated MW: 110aa, 12kDa
Storage: Store at -20C. Avoid freeze / thaw cycles.
Tissue Specificity/Positive Control:
Cellular Localization: Secreted.
Product Link: https://www.elabscience.com/p-ins_monoclonal_antibody-24965.html
Manual Link: https://www.elabscience.com/viewpdf-24965-elabscience-E-AB-27218.PDF