ITGAL Monoclonal AntibodyE-AB-27564
Product Type: monoclonal antibody
Clone No: Clone:564
Description: ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.
Research Areas: Cancer, Immunology, Signal transduction, Stem cells
Size: 200 uL
Gene ID: 3683
Recommended Dilutions: IHC 1:20-1:200
Immunogen: Fusion protein of CD11a/Integrin alpha-L
Formulation: PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Purification: Protein G purification
Calculated MW: 129kDa
Storage: Store at -20C. Avoid freeze / thaw cycles.
Tissue Specificity/Positive Control: Leukocytes.
Cellular Localization: Membrane.
Product Link: https://www.elabscience.com/p-itgal_monoclonal_antibody-25311.html
Manual Link: https://www.elabscience.com/viewpdf-25311-elabscience-E-AB-27564.PDF