Product Type: Antibody
Descritpion: Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Overexpression promotes programmed cell death.
Research Areas: Cancer, Cell Biology, Metabolism
Recommended Dilutions: WB 1:500-2000, IHC 1:50-300, IF 1:50-300
Size: 200 uL
Immunogen: Synthesized peptide derived from the Internal region of human Caspase-7
Formulation: PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Purification: Affinity purification
Calculated MW: 34kDa
Tissue Specificity/Positive Control: Highly expressed in lung, skeletal muscle, liver, kidney, spleen and heart, and moderately in testis. No expression in the brain.
Cellular Localization: Cytoplasm.
Storage: Store at -20C. Avoid freeze / thaw cycles.