Histone H3 Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Applications: WB,ELISA
Recommended Dilutions: WB 1:500-1:2000, ELISA 1:20000
Size: 200 uL
Concentration: 1mg/mL
Swissprot: P68431,Q71DI3,P84243,Q6NXT2
Gene Accession:
Reactivity: Human,Mouse,Rat
Host: Rabbit
Isotype: IgG
Immunogen: Synthesized peptide derived from human Histone H3 around the non-methylation site of K10.
Formulation: PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 15kDa
Tissue Specificity/Positive Control: Specifically expressed in the seminiferous tubules of testis
Cellular Localization: Extracellular region or secreted,extracellular exosome,extracellular region,Nucleus,nuclear chromosome,nuclear chromosome, telomeric region,nuclear nucleosome,nucleoplasm,nucleus,Other locations:nucleosome,protein complex
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-histone_h3_polyclonal_antibody-26503.html
Manual Link: https://www.elabscience.com/viewpdf-26503-elabscience-E-AB-30178.PDF