Product Type: Antibody
Descritpion: The protein encoded by this gene is a member of the interleukin 1 cytokine family. Protein structure modeling indicated that this cytokine may contain a 12-stranded beta-trefoil structure that is conserved between IL1A (IL-A alpha) and IL1B (IL-1 beta). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.IL36B (Interleukin 36, Beta) is a Protein Coding gene. Among its related pathways are Innate Immune System and Toll-Like receptor Signaling Pathways. GO annotations related to this gene include cytokine activity and interleukin-1 receptor binding. An important paralog of this gene is IL36A.
Research Areas: Immunology
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000-1:20000
Size: 200 uL
Immunogen: Synthesized peptide derived from the C-terminal region of human IL-1F8.
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Calculated MW: 19kDa
Tissue Specificity/Positive Control: Expression at low levels in tonsil, bone marrow, heart, placenta, lung, testis and colon but not in other tissues or in any hematopoietic cell lines.
Cellular Localization: Secreted.
Storage: Store at -20C. Avoid freeze / thaw cycles.