ADCY5/6 Polyclonal Antibody

ADCY5/6 Polyclonal Antibody

E-AB-30377

Regular price $399.00 $349.00 You Pay

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: ADCY5 (Adenylate Cyclase 5) is a Protein Coding gene. Diseases associated with ADCY5 include Dyskinesia, Familial, With Facial Myokymia and Chorea, Hereditary Benign. Among its related pathways are Signaling in Gap Junctions and Development Endothelin-1/EDNRA signaling. GO annotations related to this gene include protein heterodimerization activity and phosphorus-oxygen lyase activity. An important paralog of this gene is ADCY6.
ADCY6 (Adenylate Cyclase 6) is a Protein Coding gene. Diseases associated with ADCY6 include Lethal Congenital Contracture Syndrome 8 and Hypomyelination Neuropathy-Arthrogryposis Syndrome. Among its related pathways are Signaling in Gap Junctions and Development Endothelin-1/EDNRA signaling. GO annotations related to this gene include protein kinase binding and adenylate cyclase activity. An important paralog of this gene is ADCY5.
Research Areas: Cancer, Metabolism, Signal transduction
Applications: WB,IHC-p,IF,ELISA
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
Size: 200 uL
Concentration: 1mg/mL
Swissprot: O95622,O43306
Gene Accession:
Reactivity: Human,Mouse,Rat
Host: Rabbit
Isotype: IgG
Immunogen: Synthesized peptide derived from the C-terminal region of human A Cyclase V/VI
Formulation: PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 139kDa
Tissue Specificity/Positive Control: ADCY5 is Detected in pancreas islets (at protein level). Detected in pancreas islets.1 PublicationADCY6 isDetected in peripheral blood mononuclear leukocytes (at protein level) (PubMed:17916776). Detected in thyroid (PubMed:10978539).1 Publication
Cellular Localization: Cytoskeleton,intermediate filament cytoskeleton,Cytosol,guanylate cyclase complex, soluble,Plasma Membrane,Other locations:cilium,integral component of membrane
Storage: Store at -20C. Avoid freeze / thaw cycles.

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Manual Link: https://www.elabscience.com/viewpdf-26702-elabscience-E-AB-30377.PDF