AK6 Polyclonal AntibodyE-AB-30452
Product Type: Antibody
Descritpion: This gene encodes a protein that belongs to the adenylate kinase family of enzymes. The protein has a nuclear localization and contains Walker A (P-loop) and Walker B motifs and a metal-coordinating residue. The protein may be involved in regulation of Cajal body formation. In human, AK6 and TAF9 (GeneID: 6880) are two distinct genes that share 5' exons. Alternative splicing results in multiple transcript variants.AK6 (Adenylate Kinase 6) is a Protein Coding gene. Among its related pathways are Ribosome biogenesis in eukaryotes and Purine metabolism (REACTOME). GO annotations related to this gene include ATPase activity and adenylate kinase activity.
Research Areas: Epigenetics and Nuclear Signaling
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
Size: 200 uL
Immunogen: Synthesized peptide derived from the N-terminal region of human AK6
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Calculated MW: 20kDa
Tissue Specificity/Positive Control: Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, chorionic villi and the central nervous system.
Cellular Localization: Nucleus>nucleoplasm. Nucleus>Cajal body. Displays widespread diffuse nucleoplasmic distribution but not detected in nucleoli. Detected in Cajal bodies but not in all cells.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-ak6_polyclonal_antibody-26777.html
Manual Link: https://www.elabscience.com/viewpdf-26777-elabscience-E-AB-30452.PDF