RBM5 Polyclonal AntibodyE-AB-31949
Product Type: Antibody
Descritpion: This gene is a candidate tumor suppressor gene which encodes a nuclear RNA binding protein that is a component of the spliceosome A complex. The encoded protein plays a role in the induction of cell cycle arrest and apoptosis through pre-mRNA splicing of multiple target genes including the tumor suppressor protein p53. This gene is located within the tumor suppressor region 3p21.3, and may play a role in the inhibition of tumor transformation and progression of several malignancies including lung cancer.
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Size: 200 uL
Immunogen: Synthesized peptide derived from the Internal region of human LUCA15
Formulation: PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Purification: Affinity purification
Calculated MW: 92kDa
Tissue Specificity/Positive Control: Isoform 5 is widely expressed in normal tissues and is expressed at increased levels in T-leukemic cell lines.
Cellular Localization: Nucleus.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-rbm5_polyclonal_antibody-28274.html
Manual Link: https://www.elabscience.com/viewpdf-28274-elabscience-E-AB-31949.PDF