MYOM2 Polyclonal AntibodyE-AB-32145
Product Type: Antibody
Descritpion: The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD and 165 kD. The predicted MYOM2 protein contains 1,465 amino acids. Like MYOM1, MYOM2 has a unique N-terminal domain followed by 12 repeat domains with strong homology to either fibronectin type III or immunoglobulin C2 domains. Protein sequence comparisons suggested that the MYOM2 protein and bovine M protein are identical.MYOM2 (Myomesin 2) is a Protein Coding gene. Diseases associated with MYOM2 include Rheumatic Fever and Plasma Cell Neoplasm. GO annotations related to this gene include structural constituent of muscle. An important paralog of this gene is MYOM1.
Research Areas: Cardiovascular, Signal transduction, Stem cells
Recommended Dilutions: WB 1:500-1:2000, ELISA 1:40000
Size: 200 uL
Immunogen: Synthesized peptide derived from the Internal region of human Myomesin-2
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Calculated MW: 165kDa
Tissue Specificity/Positive Control:
Cellular Localization: Cytoskeleton,muscle myosin complex,myosin filament,Mitochondrion,Other locations:M band,Z disc
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-myom2_polyclonal_antibody-28470.html
Manual Link: https://www.elabscience.com/viewpdf-28470-elabscience-E-AB-32145.PDF