Product Type: Antibody
Descritpion: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.
Research Areas: Cancer, Metabolism, Neuroscience
Recommended Dilutions: WB 1:500-2000, IHC 1:50-300, IF 1:50-1:200, ELISA 1:10000-20000
Size: 200 uL
Immunogen: Synthesized peptide derived from human NOS2 around the non-phosphorylation site of Tyr151.
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Calculated MW: 131kDa
Tissue Specificity/Positive Control: Expressed in the liver, retina, bone cells and airway epithelial cells of the lung. Not expressed in the platelets.
Cellular Localization: Cytoskeleton,cortical cytoskeleton,Cytosol,Nucleus,Peroxisome,peroxisome,Other locations:cytoplasm,intracellular,perinuclear region of cytoplasm
Storage: Store at -20C. Avoid freeze / thaw cycles.