PAX8 Polyclonal AntibodyE-AB-32511
Product Type: Antibody
Descritpion: This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described.
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Neuroscience
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Size: 200 uL
Immunogen: Synthesized peptide derived from the Internal region of human Pax-8.
Formulation: PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Purification: Affinity purification
Calculated MW: 48kDa
Tissue Specificity/Positive Control: Expressed in the excretory system, thyroid gland and Wilms tumors.
Cellular Localization: Nucleus.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-pax8_polyclonal_antibody-28836.html
Manual Link: https://www.elabscience.com/viewpdf-28836-elabscience-E-AB-32511.PDF