KAT2B Polyclonal AntibodyE-AB-32520
Product Type: Antibody
Descritpion: Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes.
Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Microbiology
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Size: 200 uL
Immunogen: Synthesized peptide derived from the C-terminal region of human PCAF
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Calculated MW: 93kDa
Tissue Specificity/Positive Control: Ubiquitously expressed but most abundant in heart and skeletal muscle.
Cellular Localization: Nucleus.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-kat2b_polyclonal_antibody-28845.html
Manual Link: https://www.elabscience.com/viewpdf-28845-elabscience-E-AB-32520.PDF