Proliferating Cell Nuclear Antigen Polyclonal AntibodyE-AB-32521
Product Type: Antibody
Descritpion: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2.
Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Tags & Cell Markers
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
Size: 200 uL
Immunogen: Synthesized peptide derived from the Internal region of human PCNA
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Calculated MW: 29kDa
Tissue Specificity/Positive Control:
Cellular Localization: Nucleus
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-proliferating_cell_nuclear_antigen_polyclonal_antibody-28846.html
Manual Link: https://www.elabscience.com/viewpdf-28846-elabscience-E-AB-32521.PDF