PDGFA Polyclonal AntibodyE-AB-32528
Product Type: Antibody
Descritpion: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer or as a heterodimer with the platelet-derived growth factor beta polypeptide, where the dimers are connected by disulfide bonds. Studies using knockout mice have shown cellular defects in oligodendrocytes, alveolar smooth muscle cells, and Leydig cells in the testis; knockout mice die either as embryos or shortly after birth. Two splice variants have been identified for this gene.
Research Areas: Cancer, Cardiovascular, Metabolism, Immunology, Signal transduction
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
Size: 200 uL
Immunogen: Synthesized peptide derived from the Internal region of human PDGF-A.
Formulation: PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Purification: Affinity purification
Calculated MW: 24kDa
Tissue Specificity/Positive Control:
Cellular Localization: Secreted.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-pdgfa_polyclonal_antibody-28853.html
Manual Link: https://www.elabscience.com/viewpdf-28853-elabscience-E-AB-32528.PDF