PEX3 Polyclonal Antibody

PEX3 Polyclonal Antibody

E-AB-32551

Regular price $399.00 $349.00 You Pay

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: The product of this gene is involved in peroxisome biosynthesis and integrity. It assembles membrane vesicles before the matrix proteins are translocated. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause Zellweger syndrome (ZWS).
Research Areas: Signal transduction
Applications: WB,ELISA
Recommended Dilutions: WB 1:500-1:2000, ELISA 1:10000
Size: 200 uL
Concentration: 1mg/mL
Swissprot: P56589
Gene Accession:
Reactivity: Human,Mouse,Rat
Host: Rabbit
Isotype: IgG
Immunogen: Synthesized peptide derived from the N-terminal region of human Peroxin 3
Formulation: PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 42kDa
Tissue Specificity/Positive Control: Found in all examined tissues.
Cellular Localization: Peroxisome membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-pex3_polyclonal_antibody-28876.html
Manual Link: https://www.elabscience.com/viewpdf-28876-elabscience-E-AB-32551.PDF