PFKFB1 Polyclonal AntibodyE-AB-32557
Product Type: Antibody
Descritpion: This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene.
Research Areas: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal transduction
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000
Size: 200 uL
Immunogen: Synthesized peptide derived from the C-terminal region of human PFK-2 liv
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Calculated MW: 55kDa
Tissue Specificity/Positive Control: Liver.
Cellular Localization: Cytosol,6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex,cytosol
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-pfkfb1_polyclonal_antibody-28882.html
Manual Link: https://www.elabscience.com/viewpdf-28882-elabscience-E-AB-32557.PDF