PTGES Polyclonal AntibodyE-AB-32563
Product Type: Antibody
Descritpion: The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses.PTGES (Prostaglandin E Synthase) is a Protein Coding gene. Diseases associated with PTGES include Arthritis and Necrotizing Ulcerative Gingivitis. Among its related pathways are Ibuprofen Pathway, Pharmacodynamics and Arachidonic acid metabolism. GO annotations related to this gene include glutathione binding and prostaglandin-E synthase activity. An important paralog of this gene is MGST1.
Research Areas: Cancer, Immunology, Signal transduction
Recommended Dilutions: WB 1:500-1:2000, ELISA 1:10000
Size: 200 uL
Immunogen: Synthesized peptide derived from the Internal region of human PGE synthase.
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Calculated MW: 17kDa
Tissue Specificity/Positive Control:
Cellular Localization: Membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-ptges_polyclonal_antibody-28888.html
Manual Link: https://www.elabscience.com/viewpdf-28888-elabscience-E-AB-32563.PDF