POLR3A Polyclonal AntibodyE-AB-32632
Product Type: Antibody
Descritpion: The protein encoded by this gene is the catalytic component of RNA polymerase III, which synthesizes small RNAs. The encoded protein also acts as a sensor to detect foreign DNA and trigger an innate immune response.POLR3A (RNA Polymerase III Subunit A) is a Protein Coding gene. Diseases associated with POLR3A include Leukodystrophy, Hypomyelinating, 7, With Or Without Oligodontia And/Or Hypogonadotropic Hypogonadism and Pol Iii-Related Leukodystrophies. Among its related pathways are Innate Immune System and RNA Polymerase III Transcription Initiation. GO annotations related to this gene include chromatin binding and RNA polymerase III activity.
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
Size: 200 uL
Immunogen: Synthesized peptide derived from the N-terminal region of human POLR3A
Formulation: PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Purification: Affinity purification
Calculated MW: 156kDa
Tissue Specificity/Positive Control: Expressed in the brain, in the cortex and the white matter (at protein level).
Cellular Localization: Nucleus.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-polr3a_polyclonal_antibody-28957.html
Manual Link: https://www.elabscience.com/viewpdf-28957-elabscience-E-AB-32632.PDF