PPP2R5D Polyclonal AntibodyE-AB-32640
Product Type: Antibody
Descritpion: The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a delta isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified.PPP2R5D (Protein Phosphatase 2 Regulatory Subunit B'Delta) is a Protein Coding gene. Diseases associated with PPP2R5D include Mental Retardation, Autosomal Dominant 35 and Retinitis Pigmentosa 23. Among its related pathways are RET signaling and Activated TLR4 signalling. GO annotations related to this gene include binding. An important paralog of this gene is PPP2R5C.
Research Areas: Cancer, Neuroscience, Signal transduction
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Size: 200 uL
Immunogen: Synthesized peptide derived from the C-terminal region of human PP2A-B56-?
Formulation: PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Purification: Affinity purification
Calculated MW: 70kDa
Tissue Specificity/Positive Control: Isoform Delta-2 is widely expressed. Isoform Delta-1 is highly expressed in brain.
Cellular Localization: Cytoplasm. Nucleus. Nuclear in interphase, nuclear during mitosis.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-ppp2r5d_polyclonal_antibody-28965.html
Manual Link: https://www.elabscience.com/viewpdf-28965-elabscience-E-AB-32640.PDF