PPP2CA Polyclonal AntibodyE-AB-32641
Product Type: Antibody
Descritpion: This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit.
Research Areas: Cancer, Cell Biology, Signal transduction
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
Size: 200 uL
Immunogen: Synthesized peptide derived from human PP2A-C? around the non-phosphorylation site of Tyr307.
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Calculated MW: 36kDa
Tissue Specificity/Positive Control:
Cellular Localization: Cytoplasm. Nucleus. Chromosome>centromere. Cytoplasm>cytoskeleton>spindle pole. In prometaphase cells, but not in anaphase cells, localizes at centromeres. During mitosis, also found at spindle poles. Centromeric localization requires the presence of SGOL2.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-ppp2ca_polyclonal_antibody-28966.html
Manual Link: https://www.elabscience.com/viewpdf-28966-elabscience-E-AB-32641.PDF