ANP32C Polyclonal AntibodyE-AB-32644
Product Type: Antibody
Descritpion: Phosphoprotein 32 (PP32) is a tumor suppressor that can inhibit several types of cancers, including prostate and breast cancers. The protein encoded by this gene is one of at least two proteins that are similar in amino acid sequence to PP32 and are part of the same acidic nuclear phosphoprotein gene family. However, unlike PP32, the encoded protein is tumorigenic. The tumor suppressor function of PP32 has been localized to a 25 amino acid region that is divergent between PP32 and the protein encoded by this gene. This gene does not contain introns.
Research Areas: Cancer
Recommended Dilutions: WB 1:500-1:2000, ELISA 1:10000
Size: 200 uL
Immunogen: Synthesized peptide derived from the Internal region of human PP32R1
Formulation: PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Purification: Affinity purification
Calculated MW: 27kDa
Tissue Specificity/Positive Control: Expressed in activated stem cells, such as mobilized CD34+ cells and cord blood CD34+ cells, but not in resting bone marrow CD34+ cells. Expressed in a variety of neoplastic cell lines, mainly in prostatic adenocarcinoma cell lines. Not expressed in normal prostatic tissue.
Cellular Localization: Nucleus
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-anp32c_polyclonal_antibody-28969.html
Manual Link: https://www.elabscience.com/viewpdf-28969-elabscience-E-AB-32644.PDF