PSKH1 Polyclonal AntibodyE-AB-32671
Product Type: Antibody
Descritpion: PSKH1 (Protein Serine Kinase H1) is a Protein Coding gene. Among its related pathways are mRNA Splicing - Major Pathway. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is PSKH2.
Research Areas: Epigenetics and Nuclear Signaling, Signal transduction
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
Size: 200 uL
Immunogen: Synthesized peptide derived from the Internal region of human PSK-H1
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Calculated MW: 48kDa
Tissue Specificity/Positive Control: Expressed in all tissues and cell lines tested with the highest level of abundance in testis.
Cellular Localization: Golgi apparatus. Cytoplasm>cytoskeleton>centrosome. Nucleus speckle. Endoplasmic reticulum membrane. Cell membrane. Cytoplasm. Localized in the brefeldin A-sensitive Golgi compartment, at centrosomes, in the nucleus with a somewhat speckle-like presence, membrane-associated to the endoplasmic reticulum (ER) and the plasma membrane (PM), and more diffusely in the cytoplasm. Found to concentrate in splicing factor compartments (SFCs) within the nucleus of interphase cells. The acylation-negative form may be only cytoplasmic and nuclear. Acylation seems to allow the sequestering to the intracellular membranes. Myristoylation may mediate targeting to the intracellular non-Golgi membranes and palmitoylation may mediate the targeting to the Golgi membranes. Dual acylation is required to stabilize the interaction with Golgi membranes.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-pskh1_polyclonal_antibody-28996.html
Manual Link: https://www.elabscience.com/viewpdf-28996-elabscience-E-AB-32671.PDF