PSMD11 Polyclonal AntibodyE-AB-32673
Product Type: Antibody
Descritpion: Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, PSMD11 is required for proteasome assembly. Plays a key role in increased proteasome activity in embryonic stem cells (ESCs): its high expression in ESCs promotes enhanced assembly of the 26S proteasome, followed by higher proteasome activity.
Research Areas: Cancer, Cell Biology
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Size: 200 uL
Immunogen: Synthesized peptide derived from the Internal region of human PSMD11
Formulation: PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Purification: Affinity purification
Calculated MW: 47kDa
Tissue Specificity/Positive Control: Highly expressed in embryonic stem cells (ESCs). Expression decreases as ESCs differentiate.
Cellular Localization: Nucleus. Cytoplasm>cytosol.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-psmd11_polyclonal_antibody-28998.html
Manual Link: https://www.elabscience.com/viewpdf-28998-elabscience-E-AB-32673.PDF