PTPRZ1 Polyclonal AntibodyE-AB-32685
Product Type: Antibody
Descritpion: This gene encodes a member of the receptor protein tyrosine phosphatase family. Expression of this gene is restricted to the central nervous system (CNS), and it may be involved in the regulation of specific developmental processes in the CNS. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.PTPRZ1 (Protein Tyrosine Phosphatase, Receptor Type Z1) is a Protein Coding gene. Diseases associated with PTPRZ1 include H. Pylori Infection and Hyperlysinemia. Among its related pathways are Spinal Cord Injury and Insulin receptor recycling. GO annotations related to this gene include phosphatase activity and transmembrane receptor protein tyrosine phosphatase activity. An important paralog of this gene is PTPRG.
Research Areas: Cancer, Neuroscience, Signal transduction
Recommended Dilutions: WB 1:500-1:2000, ELISA 1:5000
Size: 200 uL
Immunogen: Synthesized peptide derived from the N-terminal region of human PTP?
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Calculated MW: 255kDa
Tissue Specificity/Positive Control: Specifically expressed in the central nervous system, where it is localized in the Purkinje cell layer of the cerebellum, the dentate gyrus, and the subependymal layer of the anterior horn of the lateral ventricle. Developmentally regulated in the brain.
Cellular Localization: Membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-ptprz1_polyclonal_antibody-29010.html
Manual Link: https://www.elabscience.com/viewpdf-29010-elabscience-E-AB-32685.PDF