RAB3GAP2 Polyclonal AntibodyE-AB-32700
Product Type: Antibody
Descritpion: RAB3GAP2 is a regulatory subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Rab3 GTPase-activating complex specifically converts active Rab3-GTP to the inactive form Rab3-GDP. It is required for normal eye and brain development and may participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.
Research Areas: Developmental biology, Neuroscience, Signal transduction
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
Size: 200 uL
Immunogen: Synthesized peptide derived from the Internal region of human Rab 3 GAP p150
Formulation: PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Purification: Affinity purification
Calculated MW: 156kDa
Tissue Specificity/Positive Control: Ubiquitous.
Cellular Localization: Cytoplasmic. Note: In neurons, it is enriched in the synaptic soluble fraction.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-rab3gap2_polyclonal_antibody-29025.html
Manual Link: https://www.elabscience.com/viewpdf-29025-elabscience-E-AB-32700.PDF