RAF1 Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. Part of the Ras-dependent signaling pathway from receptors to the nucleus. Protects cells from apoptosis mediated by STK3.
Research Areas: Cancer, Cell Biology, Metabolism, Signal transduction
Applications: WB,IF,ELISA
Recommended Dilutions: WB 1:500-1:2000, IF 1:100-1:300, ELISA 1:20000
Size: 200 uL
Concentration: 1mg/mL
Swissprot: P04049
Gene Accession:
Reactivity: Human,Mouse,Rat,Monkey
Host: Rabbit
Isotype: IgG
Immunogen: Synthesized peptide derived from human Raf-1 around the non-phosphorylation site of Ser338.
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 73kDa
Tissue Specificity/Positive Control: In skeletal muscle, isoform 1 is more abundant than isoform 2.
Cellular Localization: Cytoplasm. Cell membrane. Colocalizes with RGS14 and BRAF in both the cytoplasm and membranes.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-raf1_polyclonal_antibody-29054.html
Manual Link: https://www.elabscience.com/viewpdf-29054-elabscience-E-AB-32729.PDF