RIN3 Polyclonal AntibodyE-AB-32817
Product Type: Antibody
Descritpion: Summary: This protein encoded by this gene is a member of the RIN family of Ras interaction-interference proteins, which are binding partners to the RAB5 small GTPases. The protein functions as a guanine nucleotide exchange for RAB5B and RAB31. Alternative splicing results in multiple transcript variants.RIN3 (Ras And Rab Interactor 3) is a Protein Coding gene. Diseases associated with RIN3 include Paget's Disease Of Bone. Among its related pathways are Vesicle-mediated transport and RAB GEFs exchange GTP for GDP on RABs. GO annotations related to this gene include GTPase activator activity and Rab guanyl-nucleotide exchange factor activity. An important paralog of this gene is RIN2.
Research Areas: Signal transduction
Recommended Dilutions: WB 1:500-1:2000, ELISA 1:10000
Size: 200 uL
Immunogen: Synthesized peptide derived from the Internal region of human RIN3
Formulation: PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Purification: Affinity purification
Calculated MW: 108kDa
Tissue Specificity/Positive Control: Widely expressed.
Cellular Localization: Cytoplasm. Cytoplasmic vesicle. Early endosome. Note: Activation of tyrosine phosphorylation signaling induces translocation to cytoplasmic vesicles.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-rin3_polyclonal_antibody-29142.html
Manual Link: https://www.elabscience.com/viewpdf-29142-elabscience-E-AB-32817.PDF