RIT1 Polyclonal AntibodyE-AB-32819
Product Type: Antibody
Descritpion: This gene encodes a member of a subfamily of Ras-related GTPases. The encoded protein is involved in regulating p38 MAPK-dependent signaling cascades related to cellular stress. This protein also cooperates with nerve growth factor to promote neuronal development and regeneration. Alternate splicing results in multiple transcript variants.RIT1 (Ras Like Without CAAX 1) is a Protein Coding gene. Diseases associated with RIT1 include Noonan Syndrome 8 and Noonan Syndrome 1. Among its related pathways are Trk receptor signaling mediated by the MAPK pathway and RET signaling. GO annotations related to this gene include GTP binding and calmodulin binding. An important paralog of this gene is RIT2.
Research Areas: Cell Biology, Neuroscience, Signal transduction
Recommended Dilutions: WB 1:500-1:2000, ELISA 1:10000
Size: 200 uL
Immunogen: Synthesized peptide derived from the C-terminal region of human Rit1
Formulation: PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Purification: Affinity purification
Calculated MW: 25kDa
Tissue Specificity/Positive Control: Expressed in many tissues.
Cellular Localization: Cell membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-rit1_polyclonal_antibody-29144.html
Manual Link: https://www.elabscience.com/viewpdf-29144-elabscience-E-AB-32819.PDF