RNF130 Polyclonal AntibodyE-AB-32822
Product Type: Antibody
Descritpion: The protein encoded by this gene contains a RING finger motif and is similar to g1, a Drosophila zinc-finger protein that is expressed in mesoderm and involved in embryonic development. The expression of the mouse counterpart was found to be upregulated in myeloblastic cells following IL3 deprivation, suggesting that this gene may regulate growth factor withdrawal-induced apoptosis of myeloid precursor cells. Alternative splicing results in multiple transcript variants. RNF130 (Ring Finger Protein 130) is a Protein Coding gene. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. GO annotations related to this gene include ligase activity and ubiquitin-protein transferase activity. An important paralog of this gene is RNF150.
Research Areas: Cell Biology
Recommended Dilutions: WB 1:500-1:2000, ELISA 1:5000
Size: 200 uL
Immunogen: Synthesized peptide derived from the C-terminal region of human RNF130
Formulation: PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Purification: Affinity purification
Calculated MW: 31kDa
Tissue Specificity/Positive Control: Ubiquitously expressed. Highly expressed in leukocytes. Not expressed in erythroblasts.
Cellular Localization: Membrane; single-pass type I membrane protein
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-rnf130_polyclonal_antibody-29147.html
Manual Link: https://www.elabscience.com/viewpdf-29147-elabscience-E-AB-32822.PDF