SEPT1 Polyclonal AntibodyE-AB-32871
Product Type: Antibody
Descritpion: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined.SEPT1 (Septin 1) is a Protein Coding gene. Among its related pathways are Aurora B signaling and Bacterial invasion of epithelial cells. GO annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is SEPT4.
Research Areas: Cancer, Cell Biology, Immunology, Neuroscience
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
Size: 200 uL
Immunogen: Synthesized peptide derived from the Internal region of human Septin 1
Formulation: PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Purification: Affinity purification
Calculated MW: 42kDa
Tissue Specificity/Positive Control: Expressed at high levels in lymphoid and haematopoietic tissues.
Cellular Localization: Cytoplasm. Cytoplasm>cytoskeleton. Cytoplasm>cytoskeleton>centrosome. Remains at the centrosomes and the nearby microtubules throughout mitosis. Localizes to the midbody during cytokinesis.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-sept1_polyclonal_antibody-29196.html
Manual Link: https://www.elabscience.com/viewpdf-29196-elabscience-E-AB-32871.PDF