GPM6A Polyclonal AntibodyE-AB-33316
Product Type: Antibody
Descritpion: Neuronal membrane glycoprotein M6-a is a protein that in humans is encoded by the GPM6A gene. Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca2+ influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.
Research Areas: Neuroscience
Recommended Dilutions: WB 1:500-1:2000, ELISA 1:5000
Size: 200 uL
Immunogen: Synthesized peptide derived from the Internal region of human M6A
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Calculated MW: 31kDa
Tissue Specificity/Positive Control:
Cellular Localization: Membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-gpm6a_polyclonal_antibody-29641.html
Manual Link: https://www.elabscience.com/viewpdf-29641-elabscience-E-AB-33316.PDF