SOX-17 Polyclonal AntibodyE-AB-33325
Product Type: Antibody
Descritpion: This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins.SOX17 (SRY-Box 17) is a Protein Coding gene. Diseases associated with SOX17 include Vesicoureteral Reflux 3 and Familial Vesicoureteral Reflux. Among its related pathways are Mesodermal Commitment Pathway and Signaling by Wnt. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and protein heterodimerization activity. An important paralog of this gene is SOX7.
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Developmental biology, Stem cells
Recommended Dilutions: WB 1:500-1:2000, ELISA 1:20000
Size: 200 uL
Immunogen: Synthesized peptide derived from the Internal region of human Sox-17
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Calculated MW: 44kDa
Tissue Specificity/Positive Control: Expressed in adult heart, lung, spleen, testis, ovary, placenta, fetal lung, and kidney. In normal gastrointestinal tract, it is preferentially expressed in esophagus, stomach and small intestine than in colon and rectum.
Cellular Localization: Nucleus.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-sox_17_polyclonal_antibody-29650.html
Manual Link: https://www.elabscience.com/viewpdf-29650-elabscience-E-AB-33325.PDF